Advanced

AJNR - American Journal of Neuroradiology

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Duncan, I. C. Articles by Van Der Nest, L. Search for Related Content PubMed PubMed Citation Articles by Duncan, I. C. Articles by Van Der Nest, L.

American Journal of Neuroradiology 25:1144-1146, August 2004
© 2004 American Society of Neuroradiology

INTERVENTIONAL

Intralesional Bleomycin Injections for the Palliation of Epistaxis in Hereditary Hemorrhagic Telangiectasia

Ian C. Duncan^a and Leon Van Der Nest^b

^a Unitas Interventional Unit, Centurion, South Africa
^b Olivedale Clinic, Randburg, South Africa

Address reprint requests to Ian C. Duncan, Unitas Interventional Unit, PO Box 14031, Lyttelton, 0140, South Africa

Summary: Epistaxis is a common complication in patients with hereditary hemorrhagic telangiectasia. Its treatment is generally aimed at controlling the frequency and severity of nasal hemorrhage and involves surgery, transcatheter embolization, topical treatment, or a combination. Despite this multitude of treatment methods, the long-term prognosis for many patients remains poor. We describe a patient in whom direct intralesional injections of bleomycin successfully palliated severe recurrent epistaxis for almost 2 years without the need for adjuvant therapy.

This article has been cited by other articles:

				P.W.A. Willems, R.I. Farb, and R. Agid Endovascular Treatment of Epistaxis AJNR Am. J. Neuroradiol., October 1, 2009; 30(9): 1637 - 1645. [Abstract] [Full Text] [PDF]

				K.F. Layton, D.F. Kallmes, L.A. Gray, and H.J. Cloft Endovascular Treatment of Epistaxis in Patients with Hereditary Hemorrhagic Telangiectasia AJNR Am. J. Neuroradiol., May 1, 2007; 28(5): 885 - 888. [Abstract] [Full Text] [PDF]