Advanced

AJNR - American Journal of Neuroradiology

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Lubicz, B. Articles by Pruvo, J.-P. Search for Related Content PubMed PubMed Citation Articles by Lubicz, B. Articles by Pruvo, J.-P.

American Journal of Neuroradiology 25:1368-1372, September 2004
© 2004 American Society of Neuroradiology

INTERVENTIONAL

Selective Endovascular Treatment of Intracranial Aneurysms with Sapphire Coils

Boris Lubicz^a, Xavier Leclerc^a, Jean-Yves Gauvrit^a, Jean-Paul Lejeune^b and Jean-Pierre Pruvo^a

^a Department of Neuroradiology, Roger Salengro Hospital, University Hospital of Lille, France
^b Department of Neurosurgery, Roger Salengro Hospital, University Hospital of Lille, France

Address reprint requests to Boris Lubicz (EA 2691), Service de Neuroradiologie (Professeur Pruvo), Hôpital Roger Salengro, C.H.R.U. Lille, Boulevard J. Leclercq, 59037 Lille Cédex, France

BACKGROUND AND PURPOSE: Endovascular treatment with detachable coils is an accepted alternative to surgical clip placement for intracranial aneurysms. The purpose of this study was to evaluate the safety and reliability of the Sapphire coil, a new platinum coil for the treatment of intracranial aneurysms.

METHODS: Between August and September 2003, 20 consecutive patients (13 women, seven men; mean age, 49 years; range, 33–77 years) with 20 intracranial aneurysms were referred to our department for endovascular treatment. Fifteen patients presented with subarachnoid hemorrhage, whereas five had asymptomatic, unruptured aneurysms. All patients were treated by selective endosaccular coil placement with the new coils. The remodeling technique was used in five wide-neck aneurysms. Clinical outcomes were assessed with the modified Glasgow Outcome Scale.

RESULTS: Aneurysmal occlusion with the new coils alone was successful in 16 patients and resulted in 12 complete occlusions and four neck remnants. Because of the limited Sapphire product line, additional Guglielmi detachable coils (GDCs) were required in four patients, two of whom received one 3D GDC of 3 mm diameter and two of whom received Ultra-Soft GDCs. Technical complication (stretching of a coil) occurred in one patient. Clinical outcomes were excellent in 14 patients and good in two.

CONCLUSION: Although the study was limited by its small patient population, the results show that selective endovascular treatment of intracranial aneurysms with Sapphire coils was not associated with an unexpected incidence of adverse events. Excellent anatomic and clinical results that were obtained in most patients suggest that Sapphire coils may have value in the treatment of intracranial aneurysms.

This article has been cited by other articles:

				B. Lubicz, X. Leclerc, J.-Y. Gauvrit, J.-P. Lejeune, and J.-P. Pruvo Three-Dimensional Packing with Complex Orbit Coils for the Endovascular Treatment of Intracranial Aneurysms AJNR Am. J. Neuroradiol., June 1, 2005; 26(6): 1342 - 1348. [Abstract] [Full Text] [PDF]

				D. Pelz, T. Andersson, P. Lylyk, M. Negoro, and M. Soderman Stroke Review: Advances in Interventional Neuroradiology 2004 Stroke, February 1, 2005; 36(2): 211 - 214. [Full Text] [PDF]