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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 26:156-159, January 2005
© 2005 American Society of Neuroradiology

Case Report
BRAIN

De Novo Development of a Lesion with the Appearance of a Cavernous Malformation Adjacent to an Existing Developmental Venous Anomaly

Norbert G. Campeau^a and John I. Lane^a

^a From the Department of Radiology, Mayo Clinic, Rochester MN

Address correspondence to Norbert G. Campeau, East 2 Mayo Building, Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester MN 55905

Summary: A case is presented in which a complex multicystic hemosiderin-containing lesion developed adjacent to a previously documented developmental venous anomaly (venous angioma). This lesion had the characteristic MR imaging appearance of a cavernous malformation. Follow-up MR imaging demonstrated a decrease in both the size and complexity of this lesion, which suggests at least a portion of the lesion was due to sequelae of hemorrhage. This case further supports the association of a de novo, hemosiderin-containing lesion in association with developmental venous anomaly. Implications of these findings are that the commonly seen "cavernous malformations" in association with developmental venous anomaly are acquired lesions, and not congenital in origin. A review of the literature discussing the etiology of cavernous malformations and their reported association with the developmental venous anomaly is provided.

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