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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 26:835-838, April 2005
© 2005 American Society of Neuroradiology

Case Report
BRAIN

MR Features of Cerebral Aspergillosis in an Immunocompetent Patient: Correlation with Histology and Elemental Analysis

Warinthorn Phuttharak^a, John R. Hesselink^a and Christopher Wixom^b

^a Department of Radiology, University of California, San Diego, San Diego, CA
^b Department of Pathology, University of California, San Diego, San Diego, CA

Address correspondence to John R. Hesselink, MD, Department of Radiology, UCSD Medical Center, 200 West Arbor Drive, San Diego, CA 92103-8756

Summary: We report an unusual case of cerebral aspergillosis in a young immunocompetent patient who also had dissemination to other end organs. The patient presented with a large mass in the left cerebral hemisphere. Elemental analysis of biopsy specimens revealed elevated levels of iron, magnesium, zinc, calcium, chromium, and nickel that correlated with a peripheral rim of hypointensity on T2-weighted images.

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