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American Journal of Neuroradiology 26:1158-1162, May 2005
© 2005 American Society of Neuroradiology

Case Report
BRAIN

Radiation-Induced Cavernomas of the Brain

Rajan Jaina, Patricia L. Robertsonb, Dheeraj Gandhia, Sachin K. Gujara, Karin M. Muraszkoc and Stephen Gebarskia

a Department of Radiology, University of Michigan Medical School, Ann Arbor, MI
b Department of Neurology, University of Michigan Medical School, Ann Arbor, MI
c Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, MI

Address correspondence to Rajan Jain, MD, Division of Neuroradiology, Department of Radiology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, MI 48202

Summary: The purpose of this report is to add support to the growing literature that there is a correlation between radiation and cavernomas of the brain, particularly if the radiation is received in childhood, as well as to increase awareness of this correlation in the radiology community. Retrospective review of our experience returned five patients who received radiation therapy while they were children and developed cavernomas in the irradiated tissues 3–41 years later. Cavernomas should be considered in the differential diagnosis of a hemorrhagic lesion in any patient who has received previous CNS radiation, particularly if he or she underwent radiation therapy in childhood.




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Copyright © 2010 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X