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Case Report
PEDIATRICS

Application of Transcranial Doppler Sonography in Children with Acute Neurologic Events due to Primary Cerebral and West Nile Vasculitis

Lisa H. Lowea, Frank P. Morelloa, Mary A. Jacksonb and Andrew Laskyc

a Department of Radiology, Children’s Mercy Hospitals & Clinics, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108
b Department of Infectious Diseases, Children’s Mercy Hospitals & Clinics, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108
c Department of Rheumatology, Children’s Mercy Hospitals & Clinics, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108

Address correspondence to Lisa H. Lowe, Department of Radiology, Children’s Mercy Hospitals & Clinics, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108 (e-mail: lhlowe{at}cmh.edu or lhl{at}kc.rr.com)

Summary: We describe the use of serial transcranial Doppler studies to evaluate neurovascular disease in three girls presenting with acute stroke due to primary cerebral vasculitis (n = 2) and West Nile vasculitis (n = 1). Correlation of abnormal findings on transcranial Doppler sonography was compared with those of MR angiography and conventional angiography in each child. All three girls had left middle cerebral artery infarcts on MR imaging, with an abnormal left middle cerebral artery detected by MR angiography, conventional angiography, and transcranial Doppler sonography in each child. In all three cases, findings of the transcranial Doppler sonography, MR imaging, and catheter angiography were concordant.