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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 26:2224-2228, October 2005
© 2005 American Society of Neuroradiology

BRAIN

Decreased Fractional Anisotropy of Middle Cerebellar Peduncle in Crossed Cerebellar Diaschisis: Diffusion-Tensor Imaging-Positron-Emission Tomography Correlation Study

Jinna Kim^a, Seung-Koo Lee^a, Jong Doo Lee^b, Yong Wook Kim^c and Dong Ik Kim^a

^a Department of Radiology, Yonsei University College of Medicine, Seoul, Korea
^b Department of Nuclear Medicine, Yonsei University College of Medicine, Seoul, Korea
^c Department of Rehabilitation Medicine, Yonsei University College of Medicine, Seoul, Korea

Address correspondence to Seung-Koo Lee, MD, Department of Radiology, Yonsei University College of Medicine, 134 Shinchondong, Seodaemungu, Seoul 120-752, Korea

BACKGROUND AND PURPOSE: The purpose of this study was to evaluate the clinical usefulness of diffusion tensor MR imaging (DTI) for the assessment of chronic stroke with crossed cerebellar diaschisis (CCD).

METHODS: Twenty-two patients (15 men and 7 women; mean age, 60 years) with chronic stroke (13 ischemic and 9 hemorrhagic) were evaluated by diffusion-tensor MR imaging (DTI) and ¹⁸F-fluorodeoxyglucose (FDG)-positron-emission tomography (PET). Fractional anisotropy (FA) and color-coded vector maps were generated. To evaluate afferent fiber systems to the cerebellum, the FA of the bilateral middle cerebellar peduncle (MCP) was measured. Changes of FA values in the MCP were compared against PET results.

RESULTS: In patients with a chronic infarct involving more than one-third of the unilateral hemisphere, MCP of the contralesional side showed an FA value of 0.5226 ± 0.0174, which was significantly lower than that of the ipsilesional side MCP (0.5366 ± 0.0159) (one-tail paired t test, P = .0009). On FDG-PET scan, decreased glucose metabolism was observed in the affected cerebellum in 19 patients (86.4%).

CONCLUSION: DTI can visualize an altered corticocerebellar circuit in the case of chronic stroke with CCD, which is hardly demonstrated by conventional MR images.

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