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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 27:70-73, January 2006
© 2006 American Society of Neuroradiology

TECHNICAL NOTE
BRAIN

Line-Scan Diffusion Tensor Imaging of the Posttraumatic Brain Stem: Changes with Neuropathologic Correlation

K. Yen^a, J. Weis^e,f, R. Kreis^b, E. Aghayev^a, C. Jackowski^a, M. Thali^a, C. Boesch^b, S.E. Maier^f,g, R. Dirnhofer^a and K.O. Lövblad^c,d

^a Institute of Forensic Medicine, University of Bern, Bern, Switzerland
^b Department of Clinical Research, Magnetic Resonance Spectroscopy and Methodology, University of Bern, Bern, Switzerland
^c Department of Neuroradiology, University of Bern, Bern, Switzerland
^d Department of Neuroradiology, University of Geneva, Geneva, Switzerland
^e Division of Neuropathology, University of Aachen, Aachen, Germany
^f Institute of Pathology, University of Aachen, Aachen, Germany
^g Department of Radiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Mass

Address correspondence to Kathrin Yen, MD, Institute of Forensic Medicine, University of Bern, Buehlstrasse 20, CH-3012 Bern, Switzerland

Summary: Following trauma, imaging of brain stem lesions is often inconclusive. In a man who suffered a lethal accident, postmortem MR diffusion tensor (DT) imaging of the brain and neuropathologic examination were performed. DT imaging showed a disorganization of fibers in the brain stem that was not found in 2 controls and corresponded to changes on neuropathologic correlation. Diffusion tensor imaging provides an insight into the organization of myelinated structures of the CNS, potentially allowing diagnosis of traumatic fiber tract rupture.

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