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CASE REPORT
FUNCTIONAL

Neuropsychological and Perfusion MR Imaging Correlates of Revascularization in a Case of Moyamoya Syndrome

A.L. Jeffersona,c,d, G. Glossera, J.A. Detrea,b, G. Sinsone and D.S. Liebeskinda,b,f

a Department of Neurology, University of Pennsylvania, Philadelphia, Pa
b Department of Radiology, University of Pennsylvania, Philadelphia, Pa
c the Department of Psychology, Drexel University, Philadelphia, Pa
d the Department of Neurology, Boston University School of Medicine, Boston, Mass
e the Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisc and the UCLA Stroke Center
f Department of Neurology, UCLA, Los Angeles, Calif

Please address correspondence to: Angela L. Jefferson, PhD, Alzheimer’s Disease Center, Department of Neurology, Boston University School of Medicine, Robinson Complex, Suite 7800, 715 Albany St, Boston, MA 02118-2526

SUMMARY: Serial neurocognitive and perfusion MR imaging findings are described in the perioperative course of a 48-year-old woman with a superficial temporal artery to middle cerebral artery bypass for right hemispheric ischemia due to moyamoya syndrome. Neurocognitive testing reflected both global and focal cerebrovascular dysfunction, which suggests that perfusion augmentation following surgical revascularization may engender cognitive and neurologic improvement beyond focal regions of established ischemia.