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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 27:270-273, February 2006
© 2006 American Society of Neuroradiology

CASE REPORT
HEAD AND NECK

Primary Intracranial Germinoma Presenting as a Central Skull Base Lesion

A.C. Douglas-Akinwande^a, A.A. Mourad^a, K. Pradhan^b and E.M. Hattab^c

^a Department of Radiology, Indiana University School of Medicine, Indianapolis, Ind
^b Department of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, Ind
^c Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Ind

Address correspondence to Annette C. Douglas-Akinwande, MD, Department of Radiology, Indiana University Medical Center, University Hospital 0279, 550 N. University Boulevard, Indianapolis, IN 46202

SUMMARY: We report an unusual case of primary intracranial germinoma involving the sphenoid bone and sinus. To the best of our knowledge, paranasal sinus and bone invasion of primary intracranial germinoma has not been previously reported. Recognition of this rare form of presentation by imaging is important because early radiation and chemotherapy can result in a cure of this neoplasm.