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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 27:643-647, March 2006
© 2006 American Society of Neuroradiology

Case Report
BRAIN

Rapidly Progressive Fatal Bihemispheric Infarction Secondary to Moyamoya Syndrome in Association with Graves Thyrotoxicosis

S.W. Hsu^a,d, J.C. Chaloupka^a,b and D. Fattal^c

^a Department of Radiology, Division of Interventional Neuroradiology; University of Iowa Hospitals and Clinics, Iowa City, Iowa
^b Department of Neurosurgery; University of Iowa Hospitals and Clinics, Iowa City, Iowa
^c Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City, Iowa
^d Department of Radiology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Taiwan, Republic of China

Address correspondence to ShihWei Hsu, MD, NeuroInterventional Radiology, UIHC; JPP 3893, 200 Hawkins Dr, Iowa City, IA 52242-1077

SUMMARY: Moyamoya syndrome is the secondary form of intracranial arterial occlusive diseases that produces collateral vessels from the base of brain. We report a case of Moyamoya syndrome developing in association with Graves thyrotoxicosis; as a result of its rapid progression and severe global ischemia, it was ultimately fatal. Because of the rarity of this association, we reviewed the literature in an attempt to establish possible demographic and clinical characteristics that may suggest putative mechanisms of pathogenesis.

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