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American Journal of Neuroradiology 27:919-921, April 2006
© 2006 American Society of Neuroradiology

Case Report
BRAIN

Xanthoma Disseminatum of the Central Nervous System and Cranium

I.T. Zaka, D. Altinoka, S.S.F. Neilsenb and K.K. Kisha

a Department of Radiology, Wayne State University, Detroit, Mich
b Department of Radiology, Michigan State University, Lansing, Mich

Address correspondence to Imad T. Zak, MD, Department of Radiology, Harper University Hospital, 3990 John R, Detroit, MI 48201

SUMMARY: Xanthoma disseminatum is a rare normolipemic histiocytic disorder of non-Langerhans cell origin. It is a chronic systemic disease with a benign course, characterized by disseminated, yellow-orange–colored papules on the face, flexures, and mucosal membranes. We report 3 patients with xanthoma disseminatum, who presented primarily with central nervous system disease and a multitude of imaging findings throughout the craniospinal axis.






Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X