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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 27:1123-1128, May 2006
© 2006 American Society of Neuroradiology

INTERVENTIONAL

Embolization of Acutely Ruptured and Unruptured Wide-Necked Cerebral Aneurysms Using the Neuroform2 Stent without Pretreatment with Antiplatelets: A Single Center Experience

V. Katsaridis, C. Papagiannaki and C. Violaris

From the Neurosurgical Department, Papanikolaou General Hospital, Thessaloniki, Greece

Address correspondence to Vasilios Katsaridis, MD, PhD, Neurosurgical Department, Papanikolaou General Hospital, 1, Papanikolaou Ave, Thessaloniki GR-57010, Greece

BACKGROUND AND PURPOSE: The Neuroform2 stent has been increasingly used in the stent-assisted coiling of wide-necked cerebral aneurysms, mostly after pretreatment with antiplatelet drugs. We retrospectively analyzed our results of stent-assisted coiling without pretreatment with antiplatelets.

METHODS: We used 50 Neuroform2 stents in the treatment of 54 aneurysms without pretreatment with antiplatelets. Anticoagulation included intraprocedural heparin, nadroparin for 3 days, clopidogrel for 3 months, and aspirin for 6 months.

RESULTS: Forty-nine stents were successfully deployed, and 52 of 54 aneurysms coiled (51 totally occluded and 1 subtotally). There was only one case of intraprocedural thrombus formation that was easily treated with recombinant tissue plasminogen activator. No serious hemorrhagic complications occurred during the follow-up period, and all 18 patients whose aneurysms have been controlled with angiography were found to have patent stents without stenosis and no aneurysm recanalization. No aneurysm rebleeding has occurred.

CONCLUSION: We believe that stent-assisted coiling with the Neuroform2 stent is very effective and safe without pretreatment with antiplatelets in ruptured as well as in unruptured aneurysms.

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