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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 27:1355-1356, June-July 2006
© 2006 American Society of Neuroradiology

Case Report
INTERVENTIONAL

CNS Clostridium perfringens Infection: A Rare Complication of Preoperative Embolization of Meningioma

P.-S. Yen^a, C.-c. Lin^a, C.-C. Lee^a, T. Harnod^b, T.-W. Loh^b and Y.-H. Hsu^c

^a Departments of Radiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
^b Neurosurgery, Buddhist Tzu Chi General Hospital, Hualien, Taiwan
^c Pathology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan

Address reprints requests and correspondence to Dr. Chao-chun Lin, Department of Radiology, Buddhist Tzu Chi General Hospital, 707, Section 3 Chung Yang Rd, Hualien, Taiwan

SUMMARY: Gas gangrene is a severe form of gangrene (tissue death) that usually is caused by Clostridium perfringens. It generally occurs at the site of trauma or a recent surgical wound. We report the case of a 45-year-old woman with sphenoid-ridged meningioma who received preoperative transarterial embolization with polyvinyl alcohol. The patient later developed an intratumoral C perfringens infection and died despite intensive medical care. The case represents an extremely rare complication following transarterial embolization of meningioma.