Advanced

AJNR - American Journal of Neuroradiology

This Article Figures Only Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Aralasmak, A. Articles by Yousem, D.M. Search for Related Content PubMed PubMed Citation Articles by Aralasmak, A. Articles by Yousem, D.M.

American Journal of Neuroradiology 27:1675-1677, September 2006
© 2006 American Society of Neuroradiology

Case Report
HEAD & NECK

Giant Cell Reparative Granuloma of the Sphenoid Bone

A. Aralasmak^a, N. Aygun^a, W.H. Westra^b and D.M. Yousem^a

^a Russell H. Morgan Department of Radiology and Radiological Science, Division of Neuroradiology, Johns Hopkins Hospital, Baltimore, Md
^b Department of Pathology, Johns Hopkins Hospital, Baltimore, Md

Please address correspondence to: Ayse Aralasmak, MD, 600 N Wolfe St/Phipps B-112,Baltimore, MD 21287; e-mail: aysearalasmak{at}hotmail.com

SUMMARY: We present 2 patients with giant cell reparative granuloma (GCRG) of the sphenoid bone. The first patient is an 8-year-old boy with involvement of the greater wing, and the second is a 53- year-old man with a lateral pterygoid plate mass. Both patients presented with rapid expansion of lytic bone lesions, which had solid and cystic components and lacked matrix calcification. Biopsies were indeterminate for definitive diagnoses. The radiologic appearance, location, and incidence of the lesions, and the patient’s age and medical history are helpful aids in narrowing the differential diagnosis of sphenoid bone lesions. However, the imaging and, occasionally, even the histologic findings may not suggest the specific diagnosis of GCRG, which must be added into the differential diagnosis of rapidly enlarging cystic bone lesions of the sphenoid bone.