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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 27:1729-1731, September 2006
© 2006 American Society of Neuroradiology

Case Report
PEDIATRICS

Parry-Romberg Syndrome with a Clinically Silent White Matter Lesion

A. Okumura^a, T. Ikuta^a, T. Tsuji^a, T. Kato^a, H. Fukatsu^b, S. Naganawa^b, K. Kato^b and K. Watanabe^c

^a Department of Pediatrics, Nagoya University Graduate School of Medicine, Aichi, Japan
^b Department of Radiology, Nagoya University Graduate School of Medicine, Aichi, Japan
^c Faculty of Medical Welfare, Aichi Shukutoku University, Aichi, Japan

Please address correspondence to Akihisa Okumura, MD, Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi 466-8550, Japan; e-mail: okumura{at}med.nagoya-u.ac.jp

SUMMARY: We performed a detailed neuroimaging study in a patient with Parry-Romberg syndrome. Proton MR spectroscopy demonstrated normal spectral patterns, though conventional MR imaging revealed high-intensity areas in the entire white matter in the left hemisphere. Single-photon emission tomography showed increased perfusion in the cortex of the affected hemisphere. Pyramidal tracts and optic radiations were preserved on diffusion tensor tractography. We will correlate these neuroimaging findings with normal psychomotor development in our patient.

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