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American Journal of Neuroradiology 27:1763-1765, September 2006
© 2006 American Society of Neuroradiology

Case Report
BRAIN

Reversible Delayed Posthypoxic Leukoencephalopathy

S. Molloya, C. Sohb and T.L. Williamsa

a Department of Neurology, Royal Victoria Infirmary
b Department of Neuroradiology, Newcastle General Hospital, Newcastle upon Tyne, NE4 6BE, UK

Please address correspondence to: S. Molloy, MD, Department of Neurology, Royal Victoria Infirmary, Queen Victoria Rd, Newcastle upon Tyne, NE1 4LP, England; e-mail: Sophie.molloy{at}btopenworld.com

SUMMARY: Hypoxic ischemic encephalopathy may cause early deep white matter abnormalities on MR imaging that usually progress to include gray matter and basal ganglia change. Toxic leukoencephalopathy due to heroin inhalation predominantly causes cerebellar and posterior cerebral radiologic change. Both conditions rarely present clinically and radiologically in a delayed manner with subsequent recovery. We report a case of reversible delayed posthypoxic/toxic leukoencephalopathy with no clinical or radiologic evidence of gray matter insult.




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