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American Journal of Neuroradiology 28:433-438, March 2007
© 2007 American Society of Neuroradiology

Technical Note
BRAIN

In Vivo Assessment and Visualization of Intracranial Arterial Hemodynamics with Flow-Sensitized 4D MR Imaging at 3T

S. Wetzela, S. Meckela, A. Frydrychowiczb, L. Bonatic, E.-W. Raduea, K. Schefflerd, J. Hennigb and M. Marklb

a Department of Medical Radiology, Institute of Neuroradiology, University Hospital of Basel, Basel, Switzerland
b Department of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany
c Department of Neurology, University Hospital of Basel, Basel, Switzerland
d Department of Medical Radiology, MR-Physics, University Hospital of Basel, Basel, Switzerland

Please address Correspondence to Michael Markl, PhD, University Hospital Freiburg, Department of Diagnostic Radiology, Medical Physics, Hugstetter Str 55, 79106 Freiburg, Germany; e-mail: michael.markl{at}iniklinik-freiburg.de

SUMMARY: We evaluated electrocardiogram-synchronized flow-sensitized 4-dimensional MR imaging at 3T in combination with advanced 3D visualization strategies to ascertain its feasibility for the assessment of local intracranial blood-flow patterns in vivo. In large arteries of healthy volunteers, the temporal and spatial evolution of blood flow was successfully visualized and revealed—for example, a helical flow pattern in the carotid siphon. In a patient with steno-occlusive neurovascular disease, stagnant and retrograde flow patterns were readily visible.






Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X