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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 28:447-448, March 2007
© 2007 American Society of Neuroradiology

Case Report
BRAIN

MR Regional Perfusion Imaging: Visualizing Functional Collateral Circulation

C.C.T. Lim^a,c, E.T. Petersen^a, I. Ng^b, P.Y.K. Hwang^b, F. Hui^a and X. Golay^a,d

^a Department of Neuroradiology, National Neuroscience Institute, Singapore
^b Department of Neurosurgery, National Neuroscience Institute, Singapore
^c Department of Diagnostic Radiology, Yong Loo Lin School of Medicine, National University of Singapore
^d Laboratory of Molecular Imaging, Singapore Bioimaging Consortium, A*STAR, Singapore

Please address correspondence to: C.C.T. Lim, MD, Department of Neuroradiology, National Neuroscience Institute, 11 Jalan Tan Tock Seng, Singapore 308433; e-mail: tchoyoson_lim{at}nni.com.sg

SUMMARY: We applied regional perfusion imaging (RPI), a new arterial spin-labeling MR imaging method that selectively studies regions of the brain perfused by individual carotid and basilar arteries. In a patient with cerebrovascular disease, RPI showed cerebral tissue perfused by pial collateral vessels, thereby demonstrating the relationship between anatomic and functional information, which was lacking in conventional x-ray angiography. RPI may be useful to study functional collateral circulation and hence guide therapy in ischemic disease.