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AJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology 28:759-760, April 2007
© 2007 American Society of Neuroradiology

Case Report
BRAIN

Acute Korsakoff-Like Amnestic Syndrome Resulting from Left Thalamic Infarction Following a Right Hippocampal Hemorrhage

R. Rahme^a, R. Moussa^a, A. Awada^b, I. Ibrahim^a, Y. Ali^a, J. Maarrawi^a, T. Rizk^a, G. Nohra^a, N. Okais^a and E. Samaha^a

^a Department of Neurosurgery, Hôtel-Dieu de France and Saint-Joseph University Faculty of Medicine, Beirut, Lebanon
^b Department of Neurology, Hôtel-Dieu de France and Saint-Joseph University Faculty of Medicine, Beirut, Lebanon

Please address correspondence to Ralph Rahme, MD, Department of Neurosurgery, Hôtel-Dieu de France, Ashrafieh, Beirut, Lebanon; e-mail: rrahme{at}waln.org

SUMMARY: Korsakoff-like amnestic syndromes have been rarely described following structural lesions of the central nervous system. In this report, we describe a case of acute Korsakoff-like syndrome resulting from the combination of a left anteromedian thalamic infarct and a right hippocampal hemorrhage. We also review the literature relevant to the neuropathology and pathophysiology of Korsakoff syndrome and anterograde amnesia.