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Case Report
BRAIN

Acute Korsakoff-Like Amnestic Syndrome Resulting from Left Thalamic Infarction Following a Right Hippocampal Hemorrhage

R. Rahmea, R. Moussaa, A. Awadab, I. Ibrahima, Y. Alia, J. Maarrawia, T. Rizka, G. Nohraa, N. Okaisa and E. Samahaa

a Department of Neurosurgery, Hôtel-Dieu de France and Saint-Joseph University Faculty of Medicine, Beirut, Lebanon
b Department of Neurology, Hôtel-Dieu de France and Saint-Joseph University Faculty of Medicine, Beirut, Lebanon

Please address correspondence to Ralph Rahme, MD, Department of Neurosurgery, Hôtel-Dieu de France, Ashrafieh, Beirut, Lebanon; e-mail: rrahme{at}waln.org

SUMMARY: Korsakoff-like amnestic syndromes have been rarely described following structural lesions of the central nervous system. In this report, we describe a case of acute Korsakoff-like syndrome resulting from the combination of a left anteromedian thalamic infarct and a right hippocampal hemorrhage. We also review the literature relevant to the neuropathology and pathophysiology of Korsakoff syndrome and anterograde amnesia.