AJDRAJNR - American Journal of Neuroradiology

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Technical Note
INTERVENTIONAL

Embolectomy in a Rabbit Acute Arterial Occlusion Model Using a Novel Electromechanical Extraction Device

J. Hartmana,b, W. Small, IVc, T.S. Wilsonc, J. Brocka, P.R. Buckleyc, W.J. Benettc, J.M. Logec and D.J. Maitlandc

a Department of Radiology, University of California-Davis School of Medicine, Sacramento, Calif
b Kaiser Permanente Medical Center, Sacramento, Calif
c Lawrence Livermore National Laboratory, Livermore, Calif

Please address correspondence to Duncan J. Maitland, PhD, 7000 East Ave, L-211, Livermore, CA 94550; e-mail: maitland1{at}llnl.gov

SUMMARY: A prototype endovascular electromechanical clot-extraction device was fabricated using a combination of shape memory polymer and shape memory nickel-titanium alloy (nitinol). Five embolic vascular occlusions were created in 4 rabbits by injecting thermally coagulated blood through a 4F catheter in the common carotid artery. Angiography immediately after clot injection showed complete or partial occlusion of the common carotid artery. Posttreatment angiography showed complete (2/5), partial (2/5), or no (1/5) restoration of blood flow.