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Technical Note
BRAIN

Pseudolesions Arising from Unfolding Artifacts in Diffusion Imaging with Use of Parallel Acquisition: Origin and Remedies

M.-C. Choua,b, C.-Y. Wanga,b, H.-S. Liua,b, H.-W. Chunga,b and C.-Y. Chenb

a Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan, ROC
b Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan, ROC

Address correspondence to Cheng-Yu Chen, MD, Department of Radiology, Tri-Service General Hospital and National Defense Medical Center, No. 325, Sec. 2, Cheng-Kung Road, Neihu 114, Taipei, Taiwan, ROC; e-mail: sandy0928{at}seed.net.tw

SUMMARY: Diffusion imaging acquired with echo-planar imaging (EPI) is usually performed with parallel imaging to reduce geometric distortions, especially at high fields. This study reports the occurrence of pseudolesions in EPI with parallel imaging. The unfolding artifacts are attributed as arising from a mismatch between RF sensitivity profiles and distorted acquisition data in the presence of susceptibility effects, plus strong signals on the b = 0 images. Examples of pseudolesions from the eyeballs are shown, and remedies are suggested.




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