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AJNR - American Journal of Neuroradiology

Published ahead of print on October 18, 2007
doi: 10.3174/ajnr.A0783

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American Journal of Neuroradiology 29:184-186, January 2008
© 2008 American Society of Neuroradiology

Case Report
BRAIN

Subarachnoid Hemosiderosis and Superficial Cortical Hemosiderosis in Cerebral Amyloid Angiopathy

J. Linn^a, J. Herms^b, M. Dichgans^c, H. Brückmann^a, G. Fesl^a, T. Freilinger^c and M. Wiesmann^a

Department of Neuroradiology, University of Munich, Munich, Germany
Zentrum fur Neuropathologie und Prionforschung (ZNP), University of Munich, Munich, Germany
Department of Neurology, University of Munich, Munich, Germany

Please address correspondence to Jennifer Linn, Department of Neuroradiology, University of Munich, Grosshadern, Marchioninistr 15, 81377 Munich, Germany; e-mail: linn{at}nrad.de

SUMMARY: Cerebral amyloid angiopathy (CAA) is an important cause of intracerebral hemorrhage. Its definite diagnosis still requires histopathologic demonstration of vascular amyloid. Thus, further improvement of noninvasive imaging methods would be desirable. Here we present 3 patients with histologically proved CAA, in which superficial cortical hemosiderosis and subarachnoid hemosiderosis were present in T2*-weighted MR images. Thus, we propose that these 2 findings might be valuable as noninvasive diagnostic markers for CAA.

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