AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on October 14, 2008
doi: 10.3174/ajnr.A1225
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American Journal of Neuroradiology 29:1880-1882, November-December 2008
© 2008 American Society of Neuroradiology

Case Report
BRAIN

CT and MR Imaging of Progressive Dural Involvement by Nephrogenic Systemic Fibrosis

S. Zelaskoa, M. Hollingsheada, M. Castilloa and T.W. Bouldinb

a Department of Radiology, University of North Carolina Hospital, Chapel Hill, NC
b Departments of Pathology and Laboratory Medicine, University of North Carolina Hospital, Chapel Hill, NC

Please address correspondence to Scott Zelasko, MD, Department of Radiology, CB 7510, University of North Carolina Hospital, 101 Manning Dr, Chapel Hill, NC 27514; e-mail: scott.zelasko{at}gmail.com

SUMMARY: We present a patient with progressive dural calcifications, thickening, and enhancement presumably related to the development of nephrogenic systemic fibrosis (NSF). Head CT demonstrated progressive dural calcifications, whereas MR imaging demonstrated progressive dural thickening and enhancement during a 3-year period in which the patient received several gadolinium-enhanced MR imaging studies. To the best of our knowledge, dural calcifications are the only described intracranial finding of NSF.




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