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AJNR - American Journal of Neuroradiology

Published ahead of print on November 1, 2007
doi: 10.3174/ajnr.A0802

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American Journal of Neuroradiology 29:363-365, February 2008
© 2008 American Society of Neuroradiology

Technical Note
BRAIN

Comparison of Optimized and Standard Diffusion-Weighted Imaging at 1.5T for the Detection of Acute Lesions in Patients with Transient Ischemic Attack

A. Bertrand^a, C. Oppenheim^a, C. Lamy^b, S. Rodrigo^a, O. Naggara^a, J.L. Mas^b and J.F. Meder^a

^a Department of Neuroradiology, Université Paris Descartes, Centre Hospitalier Sainte-Anne, Paris, France
^b Department of Neurology, Université Paris Descartes, Centre Hospitalier Sainte-Anne, Paris, France

Please address correspondence to Catherine Oppenheim, Departement of Neuroradiology, Université Paris Descartes, Centre Hospitalier Sainte-Anne, 1 rue Cabanis, 75014 Paris, France; e-mail: c.oppenheim{at}ch-sainte-anne.fr

SUMMARY: The high rate of normal diffusion-weighted imaging (DWI) in patients with transient ischemic attack (TIA) raises the question as to its sensitivity for detecting small ischemic lesions. We compared standard and optimized DWI in 36 consecutive patients with TIA. Optimized DWI was positive in more patients than standard DWI (19 versus 16; P < .001) and showed more lesions (56 versus 42; P = .002). At 1.5T, optimizing DWI decreases the rate of false-negative DWI in patients with TIA.