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AJNR - American Journal of Neuroradiology

Published ahead of print on January 9, 2008
doi: 10.3174/ajnr.A0924

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American Journal of Neuroradiology 29:434-435, March 2008
© 2008 American Society of Neuroradiology

Case Report
PEDIATRICS

Malignant Transformation of a Lipomyelocele into a Rhabdomyosarcoma?

A.M. O'Connell^a, D. Allcutt^b, F. Brett^c and S. Ryan^a

^a Department of Radiology, Children's University Hospital, Dublin, Ireland
^b Department of Neurosurgery, Beaumont Hospital, Dublin, Ireland
^c Department of Neuropathology, Beaumont Hospital, Dublin, Ireland

Please address correspondence to AnnaMarie O'Connell, MD, Department of Radiology, Children's University Hospital, Temple St, Dublin, Ireland; e-mail: amoconnell{at}yahoo.com

SUMMARY: We report the unusual transformation of a lipomyelocele to a rhabdomyosarcoma in a 3-year-old boy. A lipomyelocele is not considered pre-malignant, but the possibility of developing such a tumor may represent another reason for close neurological follow-up in patients with spinal dysraphism.