AJDRAJNR - American Journal of Neuroradiology

Published ahead of print on February 22, 2008
doi: 10.3174/ajnr.A1016

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Case Report
BRAIN

Sequential Pituitary MR Imaging in Sheehan Syndrome: Report of 2 Cases

J. Kapluna, C. Fratilac, A. Ferenczia, W.C. Yangb, G. Lantosd, A.M. Fleckmana and U.K. Schubartc

a Department of Medicine, Beth Israel Medical Center, University Hospital and Manhattan Campus for the Albert Einstein College of Medicine, New York, NY
b Department of Radiology, Beth Israel Medical Center, University Hospital and Manhattan Campus for the Albert Einstein College of Medicine, New York, NY
c Department of Medicine, Jacobi Medical Center, Bronx, NY
d Department of Radiology, Jacobi Medical Center, Bronx, NY

Please address correspondence to George Lantos, MD, Department of Radiology, Jacobi Medical Center, 1400 Pelham Parkway South, Bronx, NY 10461; e-mail: lantosg{at}post.harvard.edu

SUMMARY: We present the evolution of pituitary changes in the cases of 2 patients with Sheehan syndrome as assessed by MR imaging. Both patients had severe postpartum hemorrhage, symptoms of pituitary gland apoplexy, and hypopituitarism. Sequential MR imaging demonstrated evidence of ischemic infarct in the pituitary gland with enlargement followed by gradual shrinkage during several months, to pituitary atrophy.