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AJNR - American Journal of Neuroradiology

Published ahead of print on April 10, 2008
doi: 10.3174/ajnr.A1068

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American Journal of Neuroradiology 29:1414-1417, August 2008
© 2008 American Society of Neuroradiology

Case Report
INTERVENTIONAL

Local Intra-Arterial Eptifibatide for Intraoperative Vessel Thrombosis during Aneurysm Coiling

V. Katsaridis, C. Papagiannaki, N. Skoulios, I. Achoulias and D. Peios

From the Neurosurgical Department, Papanikolaou General Hospital, Thessaloniki, Greece

Please address correspondence to Vasilios Katsaridis, MD, PhD, Neurosurgical Department, Papanikolaou General Hospital, 15, Papanikolaou Ave, Thessaloniki GR-57010, Greece; e-mail: vkats{at}iname.com

SUMMARY: We report on our experience with the intra-arterial administration of eptifibatide for thrombolysis during aneurysm-embolization procedures. In 4 cases (3 stent-assisted coiling procedures and 1 with posthemorrhagic vasospasm), we noted the formation of thrombus occluding a vessel. We administered eptifibatide (10–15 mg) through a microcatheter proximal to the thrombus. The thrombus rapidly dissolved, resulting in the recanalization of the occluded vessels with no rethrombosis or hemorrhagic complications.