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AJNR - American Journal of Neuroradiology

Published ahead of print on August 7, 2008
doi: 10.3174/ajnr.A1227

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American Journal of Neuroradiology 29:1425-1427, September 2008
© 2008 American Society of Neuroradiology

Research Perspective

Toward a Uniform Policy for Handling Incidental Findings in Neuroimaging Research

D.A. Brown^a and A.N. Hasso^b

^a School of Medicine, University of California, Irvine, Orange, Calif
^b Department of Radiological Sciences, University of California, Irvine Medical Center, Orange, Calif

Please address correspondence to Anton N. Hasso, MD, FACR, Department of Radiological Sciences, University of California, Irvine Medical Center, 101 City Dr S, Orange, CA 92668-3298; e-mail: anhasso{at}uci.edu

SUMMARY: A recent study carried out at the University of California, Irvine exemplifies a commonly overlooked ethical conundrum of neuroimaging research: incidental findings. Research study designs must address the potential of uncovering unexpected findings in subjects during the study and delineate a protocol for reporting and initiating treatment. We urge the community to petition their home institutional review board to mandate inclusion of an incidental findings protocol into all neuroimaging research applications.