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AJNR - American Journal of Neuroradiology

Published ahead of print on January 8, 2009
doi: 10.3174/ajnr.A1461

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American Journal of Neuroradiology 30:232-252, February 2009
© 2009 American Society of Neuroradiology

PHYSICS REVIEW

Susceptibility-Weighted Imaging: Technical Aspects and Clinical Applications, Part 2

S. Mittal^a,d, Z. Wu^e, J. Neelavalli^b,f and E.M. Haacke^b,c,d,f

^a Department of Neurosurgery, Wayne State University, Detroit, Mich
^b Department of Biomedical Engineering, Wayne State University, Detroit, Mich
^c Department of Radiology, Wayne State University, Detroit, Mich
^d Karmanos Cancer Institute, Wayne State University, Detroit, Mich
^e School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada
^f MRI Institute for Biomedical Research, Detroit, Mich

Please address correspondence to E. Mark Haacke, PhD, Wayne State University, MR Research Facility, Department of Radiology, HUH—MR Research G030/Radiology, 3990 John R Rd, Detroit, MI 48201; e-mail: nmrimaging{at}aol.com

SUMMARY: Susceptibility-weighted imaging (SWI) has continued to develop into a powerful clinical tool to visualize venous structures and iron in the brain and to study diverse pathologic conditions. SWI offers a unique contrast, different from spin attenuation, T1, T2, and T2* (see Susceptibility-Weighted Imaging: Technical Aspects and Clinical Applications, Part 1). In this clinical review (Part 2), we present a variety of neurovascular and neurodegenerative disease applications for SWI, covering trauma, stroke, cerebral amyloid angiopathy, venous anomalies, multiple sclerosis, and tumors. We conclude that SWI often offers complementary information valuable in the diagnosis and potential treatment of patients with neurologic disorders.

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