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AJNR - American Journal of Neuroradiology

Published ahead of print on June 25, 2009
doi: 10.3174/ajnr.A1532

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American Journal of Neuroradiology 30:1409-1411, August 2009
© 2009 American Society of Neuroradiology

Case Report
BRAIN

Steroid-Responsive Large Vessel Vasculitis: Application of Whole-Brain 320-Detector Row Dynamic Volume CT Angiography and Perfusion

N. Yahyavi-Firouz-Abadi^a, B.L. Wynn^b, F.J. Rybicki^a, M.L. Steigner^a, A.Z. Hussain^a, R. Mather^c, E.H. Hanson^b,d,f, M. Ansarinia^e and W.W. Orrison, Jr.^b,d,f,g,h

^a Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women's Hospital, Boston, Mass
^b Touro University Nevada College of Osteopathic Medicine, Henderson, Nev
^c Toshiba America Medical Systems, Tustin, Calif
^d Advanced Medical Imaging and Genetics (Amigenics), Las Vegas, Nev
^e Headache Specialists, Las Vegas, Nev
^f Department of Health Physics, University of Nevada, Las Vegas, Nev
^g Nevada Imaging Centers, Las Vegas, Nev
^h University of Nevada School of Medicine, Reno, Nev

Please address correspondence to Frank J. Rybicki, MD, PhD, Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115; e-mail: frybicki{at}partners.org

SUMMARY: A patient with suspected giant cell arteritis and prior negative findings on superficial temporal artery biopsy was evaluated with 320-detector row CT angiography (CTA) and whole-brain perfusion. Corticosteroid treatment was initiated on the basis of CT angiography findings of arteritis and a cortical perfusion deficit. The patient's symptoms and perfusion imaging findings resolved following therapy. Whole-brain CTA and imaging was helpful in the diagnosis and monitoring this patient with suspected vasculitis.