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AJNR - American Journal of Neuroradiology

Published ahead of print on April 15, 2009
doi: 10.3174/ajnr.A1531

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American Journal of Neuroradiology 30:1598-1601, September 2009
© 2009 American Society of Neuroradiology

HEAD AND NECK

CT Perfusion of the Neck: Internal Carotid Artery versus External Carotid Artery as the Reference Artery

A.C. Miracle^a, A. Rezaei^a, D. Gandhi^a and S.K. Mukherji^a,b,c

^aFrom the Departments of Radiology (A.C.M., A.R., D.G., S.K.M.)
^bOtolaryngology (S.K.M.)
^cRadiation Oncology (S.K.M.), University of Michigan Health System, University Hospital, 1500 East Medical Center Dr, Ann Arbor, Mich.

Please address correspondence to Aaron C. Miracle, Department of Radiology, University of Michigan Health System, 1500 E. Medical Center Dr, B2B311 UH SPC 5030, Ann Arbor, MI 48190; e-mail: amiracle{at}med.umich.edu

SUMMARY: Arterial selection for reference time-enhancement curve generation in deconvolution-based perfusion CT (PCT) studies of the head and neck is underevaluated. This study of 11 patients with confirmed head and neck squamous cell carcinoma demonstrates significant correlation (range, r = 0.85–0.95) between perfusion parameter values derived with internal carotid artery (ICA) as compared to an external carotid artery reference, supporting the use of the ICA as arterial reference in PCT studies of the neck.