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American Journal of Neuroradiology, Vol 4, Issue 3 329-332, Copyright © 1983 by American Society of Neuroradiology

ARTICLES

Intravenous digital subtraction angiography with iohexol

ED Cacayorin, AD Bernstein, CT Fruehan, SH Lee and SA Kieffer

Iohexol is a nonionic water-soluble iodinated contrast medium with chemical and physical properties similar to those of metrizamide. A randomized double-blind study was performed in 40 patients undergoing intravenous digital subtraction angiography for suspected carotid and vertebral disease to compare the radiographic imaging quality and side effects of iohexol with those of Renografin-76 (diatrizoate meglumine and diatrizoate sodium). The use of iohexol yielded a higher percentage of "excellent" images with a lesser incidence of image degradation due to swallowing and motion. Iohexol was also associated with milder and less frequent patient discomfort. No clinically significant changes in laboratory data parameters were observed with either contrast medium.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X