AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology, Vol 4, Issue 3 347-349, Copyright © 1983 by American Society of Neuroradiology

ARTICLES

Comparative double-blind investigation of meglumine metrizoate, metrizamide, and iohexol in carotid angiography

T Hindmarsh, G Bergstrand, K Ericson and H Olivecrona

The new nonionic contrast medium iohexol (Omnipaque) was compared with its predecessor metrizamide (Amipaque) and with the conventional ionic medium meglumine metrizoate (Isopaque Cerebral) in carotid angiography using a double-blind crossover technique. The results indicated that iohexol and metrizamide caused less discomfort than the ionic medium. The circulatory effects of the three media were generally mild, and the diagnostic effectiveness was comparable when the iodine concentration was kept in the range of 280-300 mg I/ml.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X