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American Journal of Neuroradiology, Vol 4, Issue 3 385-387, Copyright © 1983 by American Society of Neuroradiology

ARTICLES

Histopathologic effects of transarterial bucrylate occlusion of intracerebral arteries in mongrel dogs

KK Kish, SM Rapp, HI Wilner, D Wolfe, LM Thomas and J Barr

Bucrylate was injected directly into the cerebral cortical arteries of mongrel dogs. Preparations for light and electron microscopy were obtained from 5 min to 5 months after the introduction of the polymer. A mixed pattern of damage to arterial endothelium was seen, including electron microscopic documentation of stripping away of the endothelium. Acute effects include a subocclusive thrombogenic matrix, which causes partial or complete thrombosis. The long-term reactions are those of a chronic inflammatory response to a foreign body.


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Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X