AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology, Vol 4, Issue 3 399-400, Copyright © 1983 by American Society of Neuroradiology

ARTICLES

Superselective injection of BCNU through a latex calibrated-leak balloon

GM Debrun, KR Davis and FH Hochberg

Carmustine (BCNU) has been used extensively to treat glioblastomas by injection through a catheter placed in the cervical internal carotid artery. The technique causes severe pain to the eye and has resulted in ipsilateral blindness. The use of a latex calibrated-leak balloon positioned above the ophthalmic artery in the internal carotid artery or in one of its branches appears to circumvent the ocular complications mentioned. At an infusion rate at 125 ml/hr the balloon does not inflate and does not occlude the artery. This new technique has been used to treat 10 patients without complications.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X