AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology, Vol 5, Issue 1 67-69, Copyright © 1984 by American Society of Neuroradiology

ARTICLES

Animal model for studying the chronic effects of herniated disks and spinal surgery

CR Barthelemy, J Johansen, GF Carrera and VM Haughton

A successful model to study both herniated intervertebral disks and spinal operations such as laminectomy has not been described. Two procedures were developed in nonhuman primates: One produces an elevated nerve root simulating a herniated disk; the second is a laminectomy that simulates the operation in humans. Twenty-five surgical procedures were performed with no complications. A myelographic abnormality typical of a disk herniation results from the simulated disk herniation. The chronic effects of herniated disk and spinal surgery can be studied with this model.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X