AJDRAJNR - American Journal of Neuroradiology

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Davis, P. C.
Right arrow Articles by Weidenheim, K. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Davis, P. C.
Right arrow Articles by Weidenheim, K. M.

American Journal of Neuroradiology, Vol 5, Issue 5 579-585, Copyright © 1984 by American Society of Neuroradiology

ARTICLES

Large hypothalamic and optic chiasm gliomas in infants: difficulties in distinction

PC Davis, JC Hoffman Jr and KM Weidenheim

Hypothalamic and optic chiasm gliomas may be indistinguishable clinically, radiographically, and pathologically. Ten children with giant gliomas of the hypothalamus and optic pathway, all under age 2 years, had masses greater than 3 cm in diameter. Pathologically all proven cases (seven) were cytologically benign fibrillary astrocytomas. Previous authors have recognized the difficulty in distinguishing these lesions; in this series, using previously suggested criteria, masses of optic chiasm could not be differentiated from hypothalamic origins. Likewise, at surgery and autopsy, the origin of these large masses was indeterminate. These tumors were more aggressive, invasive, and less responsive to therapy than the relatively benign orbital and optic nerve gliomas of older children and adults.




Copyright © 2008 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X