American Journal of Neuroradiology, Vol 7, Issue 2 343-348, Copyright © 1986 by American Society of Neuroradiology
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Intraarterial chemotherapy of head and neck tumors
YY Lee, S Wallace, I Dimery and H Goepfert
Forty-one patients with advanced recurrent or untreated and neck tumors were treated with intraarterial short-term (1-1 1/2 hr) infusion of cisplatin into the external carotid artery, achieving an immediate tumor response rate of 29.3%. Tumor extent within or beyond the territory of a single external carotid artery was the only significant factor identified affecting the tumor response rate (57.1% vs. 14.8%). Treatment with intraarterial chemotherapy using superselective catheterization before irradiation or surgery is beneficial in some patients.
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