AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology, Vol 7, Issue 3 498-501, Copyright © 1986 by American Society of Neuroradiology

ARTICLES

Myelography with metrizamide: effect of contrast removal on side effects

Y Numaguchi, AM Weems, A Mizushima, J Keating, AB Rege, FJ Mather and JC Rice

Moderately severe side effects, such as prolonged headache, nausea, vomiting, or psychoneurologic symptoms, were noted in 27 (32%) of 84 patients in whom the contrast medium was not removed. Conversely, among 73 patients from whom 20-25 ml of cerebrospinal fluid with the contrast medium was removed, only 10 (14%) experienced adverse effects, a statistically significant reduction. Although new contrast agents, such as iohexol and iopamidol, are reportedly less toxic than metrizamide, the contrast-removal technique described here may be indicated when large amounts of any contrast medium are used.




Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X