American Journal of Neuroradiology 2009;30:1409.
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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1532
BRAIN
Steroid-Responsive Large Vessel Vasculitis: Application of Whole-Brain 320-Detector Row Dynamic Volume CT Angiography and Perfusion
From Applied Imaging Science Laboratory (N.Y.-F.-A., F.J.R., M.L.S., A.Z.H.), Department of Radiology, Brigham and Women's Hospital, Boston, Mass; Touro University Nevada College of Osteopathic Medicine (B.L.W., E.H.H., W.W.O.), Henderson, Nev; Toshiba America Medical Systems (R.M.), Tustin, Calif; Advanced Medical Imaging and Genetics (Amigenics) (E.H.H., W.W.O.), Las Vegas, Nev; Headache Specialists (M.A.), Las Vegas, Nev; Department of Health Physics (E.H.H., W.W.O.), University of Nevada, Las Vegas, Nev; Nevada Imaging Centers (W.W.O.), Las Vegas, Nev; and University of Nevada School of Medicine (W.W.O.), Reno, Nev.
Please address correspondence to Frank J. Rybicki, MD, PhD, Applied Imaging Science Laboratory, Department of Radiology, Brigham and Women's Hospital, 75 Francis St, Boston, MA 02115; e-mail: frybicki{at}partners.org
SUMMARY: A patient with suspected giant cell arteritis and prior negative findings on superficial temporal artery biopsy was evaluated with 320-detector row CT angiography (CTA) and whole-brain perfusion. Corticosteroid treatment was initiated on the basis of CT angiography findings of arteritis and a cortical perfusion deficit. The patient's symptoms and perfusion imaging findings resolved following therapy. Whole-brain CTA and imaging was helpful in the diagnosis and monitoring this patient with suspected vasculitis.