AJDRAJNR - American Journal of Neuroradiology

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American Journal of Neuroradiology
DOI 10.3174/ajnr.A1671

BRAIN

Focal Neuronal Gigantism: A Rare Complication of Therapeutic Radiation

J.R. Gaughen, T.D. Bourne, D. Aregawi, L.M. Shah and D. Schiff

From the Departments of Radiology (J.R.G.), Pathology (T.D.B.), and Neurology (D.A., D.S.), University of Virginia Health System, Charlottesville, Va; and Department of Radiology (L.M.S.), University of Utah, Salt Lake City, Utah.

Please address correspondence to John R. Gaughen, Jr., MD, Department of Radiology, University of Virginia Health System, PO Box 800170, Charlottesville, VA 22908; e-mail: jrg4s{at}virginia.edu

SUMMARY: Radiation therapy, a mainstay in the treatment of many brain tumors, results in a variety of well-documented acute and chronic complications. Isolated cortical damage following irradiation represents an extremely rare delayed therapeutic complication, described only twice in the medical literature. We report this rare delayed complication in a patient following treatment of a right frontal anaplastic oligodendroglioma.






Copyright © 2009 by the American Society of Neuroradiology. Print ISSN: 0195-6108 Online ISSN: 1936-959X