Abstract
SUMMARY: DSC perfusion MR imaging in brain tumors requires a trade-off between spatial and temporal resolution, resulting in less spatial coverage to meet the temporal resolution requirements for accurate relative CBV estimation. DSC-MR imaging could potentially benefit from the advantages associated with simultaneous multi-slice imaging, including increased spatiotemporal resolution. In the current article, we demonstrate how simultaneous multi-slice EPI can be used to improve DSC-MR imaging spatiotemporal resolution in patients with glioblastoma.
ABBREVIATIONS:
- rCBV
- relative CBV
- SMS
- simultaneous multi-slice
Footnotes
Disclosures: Whitney B. Pope—RELATED: Consulting Fee or Honorarium: Bracco; UNRELATED: Grants/Grants Pending: Guerbet.* Benjamin M. Ellingson—RELATED: Grant: Siemens; UNRELATED: Board Membership: MedQIA, Medicenna, Roche, Agios Pharmaceuticals, Bristol-Myers Squib; Consultancy: MedQIA, Medicenna, Roche, Agios Pharmaceuticals, Bristol-Myers Squib. *Money paid to the institution.
This work was supported by the American Cancer Society Research Scholar Grant RSG-15-003-01-CCE (B.M.E.); the National Institutes of Health/National Cancer Institute R21CA167354 (B.M.E.); an American Brain Tumor Association Research Collaboration Grant supported by Humor to Fight the Tumor, ARC1700002 (B.M.E.); a National Brain Tumor Society research grant (B.M.E.); a National Institutes of Health/National Institute of General Medical Sciences training grant, GM08042 (K.L.); and the University of California, Los Angeles Medical Scientist Training Program (K.L.).
- © 2018 by American Journal of Neuroradiology
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