Abstract
SUMMARY: Osteoporotic vertebral compression fractures frequently result in significant morbidity and health care resource use. For patients with severe and disabling pain, vertebral augmentation (vertebroplasty and kyphoplasty) is often considered. Although vertebroplasty was introduced >30 years ago, there are conflicting opinions regarding the role of these procedures in the treatment of osteoporotic vertebral compression fractures. This review article updates clinicians on the published prospective randomized controlled data, including the most recent positive trials that followed initial negative trials in 2009. Analysis of multiple national claim datasets has also provided further insight into the utility of these procedures. Finally, we considered the recent recommendations of national organizations and medical societies that advise on the use of vertebral augmentation procedures for osteoporotic vertebral compression fractures.
ABBREVIATIONS:
- NRS
- numeric rating scale
- PMMA
- polymethylmethacrylate
- QUALEFFO
- Quality of Life Questionnaire of the European Foundation for Osteoporosis
- RCT
- randomized controlled trial
- RDQ
- Roland Morris Disability Questionnaire
- VAS
- Visual Analog Scale
- VCF
- vertebral compression fracture
Footnotes
Disclosures: Hamed Asadi—UNRELATED: Other: participated in the Interventional Neuroradiology meetings sponsored by the industry. Stefano Marcia—UNRELATED: Consultancy: Stryker, Techlamed, Vexim, Spineart. John Barr—UNRELATED: Stock/Stock Options: Medtronic, Stryker, Comments: purchased stock. Joshua A. Hirsch—UNRELATED: Board Membership: Codman Neurovascular, Comments: Data and Safety Monitoring Board; Consultancy: Medtronic, Globus, Comments: These companies make augmentation products.
- © 2018 by American Journal of Neuroradiology
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