Abstract
BACKGROUND AND PURPOSE: The Neck Imaging Reporting and Data System was introduced to assess the probability of recurrence in surveillance imaging after treatment of head and neck cancer. This study investigated inter- and intrareader agreement in interpreting contrast-enhanced CT after treatment of oral cavity and oropharyngeal squamous cell carcinoma.
MATERIALS AND METHODS: This retrospective study analyzed CT datasets of 101 patients. Four radiologists provided the Neck Imaging Reporting and Data System reports for the primary site and neck (cervical lymph nodes). The Kendall's coefficient of concordance (W), Fleiss κ (κF), the Kendall's rank correlation coefficient (τB), and weighted κ statistics (κw) were calculated to assess inter- and intrareader agreement.
RESULTS: Overall, interreader agreement was strong or moderate for both the primary site (W = 0.74, κF = 0.48) and the neck (W = 0.80, κF = 0.50), depending on the statistics applied. Interreader agreement was higher in patients with proved recurrence at the primary site (W = 0.96 versus 0.56, κF = 0.65 versus 0.30) or in the neck (W = 0.78 versus 0.56, κF = 0.41 versus 0.29). Intrareader agreement was moderate to strong or almost perfect at the primary site (range τB = 0.67–0.82, κw = 0.85–0.96) and strong or almost perfect in the neck (range τB = 0.76–0.86, κw = 0.89–0.95).
CONCLUSIONS: The Neck Imaging Reporting and Data System used for surveillance contrast-enhanced CT after treatment of oral cavity and oropharyngeal squamous cell carcinoma provides acceptable score reproducibility with limitations in patients with posttherapeutic changes but no cancer recurrence.
ABBREVIATIONS:
- BI
- Breast Imaging
- CECT
- contrast-enhanced CT
- LI
- Liver Imaging
- NI
- Neck Imaging
- OCSCC
- oral cavity squamous cell carcinoma
- OPSCC
- oropharyngeal squamous cell carcinoma
- PI
- Prostate Imaging
- RADS
- Reporting and Data System
Footnotes
Disclosures: Stefan Markus Niehues—UNRELATED: Grants/Grants Pending: German Research Foundation grant*; Payment for Lectures Including Service on Speakers Bureaus: speakers honorarium for Canon, Guerbet, Bracco, Teleflex. Bernd Hamm—UNRELATED: Grants/Grants Pending: Abbott Laboratories, Actelion Pharmaceuticals, Bayer Schering Pharma, Bayer Vital, Bracco Group, Bristol-Myers Squibb, Charité Research Organization GmbH, Deutsche Krebshilfe, Deutsche Stiftung für Herzforschung, Essex Pharma, European Union Programs, FIBREX Medical Inc, Focused Ultrasound Surgery Foundation, Fraunhofer Gesellschaft, Guerbet, INC Research, InSightec Ltd, Ipsen Biopharmaceuticals, Kendle/MorphoSys AG, Lilly Deutschland GmbH, Lundbeck GmbH, MeVis Medical Solutions AG, Nexus Oncology, Novartis, Parexel CRO Service, Perceptive Innovations, Pfizer GmbH, Philipps Healthcare, Sanofis-Aventis SA, Siemens, Spectranetics GmbH, Terumo Medical Corporation, TNS Healthcare GmbH, Toshiba, UCB, Wyeth Pharmaceuticals, Zukunftsfond Berlin/TSB Medici.* *Money paid to the institution.
- © 2020 by American Journal of Neuroradiology