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Location of the Primary Motor Cortex in Schizencephaly

Ho Kyu LeeGo,a, Jin Suh Kima, Youn Mee Hwanga, Myung Joon Leea, Choong Gon Choia, Dae Chul Suha and Tae-Hwan Lima

a From the Departments of Radiology (H.K.L., J.S.K., M.J.L., C.G.C., D.C.S., T-H.L.), Neurology (Y.M.H.), and Radiological Sciences (T-H.L.), Asan Institute for Life Sciences, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.



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FIG 1. Patient 1, with schizencephaly and agenesis of the corpus callosum and an associated interhemispheric cyst. The ipsilateral activation index on the unaffected hemisphere is infinite.

A, Functional MR image (90/56; T1-weighted image [300/14/2]) shows the widespread and lower-lying activation areas adjacent to the central sulcus (arrow) during the right-hand motor task. Arrowheads indicate schizencephaly.

B, Functional MR image (90/56; T1-weighted image [300/14/2]) shows the activation area of the left-hand motor task located in the less-affected hemisphere.



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FIG 2. Patient 3, with schizencephaly and focal cortical dysplasia. Abnormal gyral pattern is noted in the right hemisphere. Ipsilateral activation index on the unaffected hemisphere is 15.4.

A and B, Functional MR images (90/56; T1-weighted images [250/14/2]) show the activation areas located in the vicinity of the central sulcus of the unaffected hemisphere during the right-hand (arrow, A) and left-hand (B) motor tasks.