Cervical Epidural Lipoblastomatosis: Changing MR Appearance after Chemotherapy
Hussein A. M. Kamel
,a,
Paul R. Brennana and
Michael A. Farrella
a From the Department of Neuroradiology, The Royal Victoria Hospital, Belfast, United Kingdom (H.A.K.); and the Departments of Neuroradiology (P.R.B.) and Neuropathology (M.A.F.), Beaumont Hospital, Dublin, Ireland.
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FIG 1. 10-month girl with torticollis, weakness, and wasting of the muscles of the right arm.
A, Coronal T1-weighted (540/13/2) MR image shows multilobular low-signal tumor on the right side of the neck (arrowhead) and superior mediastinum. Arrow indicates physiological thymic enlargement.
B, Sagittal T2-weighted (4000/90/2) image shows high-signal-intensity multilobular tumor with low-signal septa. The tumor spreads through the intervertebral foramina (arrow).
C, Representative section from the initial resection specimen shows cells with elongated, wispy cytoplasmic processes and variably shaped nuclei. Note absence of mitotic figures (original magnification x250).
D, Coronal T1-weighted (540/13/2) follow-up MR examination shows increased signal intensity and bands of low signal within the tumor.
E, Representative section from the subsequent resection specimen shows the tumor now clearly consists of mature fat cells with relatively few nuclei (original magnification x100).
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