MR Line Scan Diffusion Imaging of the Brain in Children
Richard L. Robertson
,a,
Stephan E. Maiera,
Caroline D. Robsona,
Robert V. Mulkerna,
Palagia M. Karasa and
Patrick D. Barnesa
a From the Department of Radiology, Children's Hospital Medical Center and Harvard Medical School (R.L.R., C.D.R., R.V.M., P.M.K., P.D.B.); and the Department of Radiology, Brigham and Women's Hospital and Harvard Medical School (S.E.M.), Boston.
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FIG 1. EPID versus LSDI in a healthy volunteer.
A and B, EPID (2000/90/1; b = 600 s/mm2) trace images at two anatomic levels show geometric distortion of the brain stem and artifactual high signal intensity in the temporal lobes and anterior frontal lobes.
C and D, LSDI (2736/89/1; b = 600 s/mm2) trace images at corresponding levels show less geometric distortion and less magnetic-susceptibility artifact.
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FIG 2. EPID versus LSDI in a volunteer with a paper clip taped to the forehead.
A, EPID (2000/90/1; b = 600 s/mm2) trace image shows marked signal loss due to magnetic-susceptibility effect in the anterior two thirds of the brain.
B, LSDI (2736/89/1; b = 600 s/mm2) trace image at the same level shows less artifactual signal loss with preservation of much of the anatomic detail.
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FIG 3. Case 1: Neonate with hypoplastic left heart and seizures due to embolic infarction.
A, Three hyperintense lesions (arrows) are evident on the T2-weighted (3200/85/1) image.
B, The lesions are more conspicuous on the LSDI (2736/89/1; b = 600 s/mm2) trace image.
C, The lesions have decreased ADCs, as shown by low intensity on the diffusion map.
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FIG 4. Case 8: 11 year-old boy with new left hemiparesis due to emboli from a vertebral artery dissection.
A–C, A left thalamocapsular lesion is evident on the T2-weighted (3200/85/1) image (arrow, A). The lesion is more conspicuous on the LSDI (2736/89/1; b = 600 s/mm2) trace image (arrow, B), and has a decreased ADC on the diffusion map (C), indicating an acute infarction.
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FIG 5. Case 5: 2-year-old girl with left-sided body seizures due to encephalitis.
A–C, A minimally hyperintense lesion is present in the right thalamus on the T2-weighted (3200/85/1) image (arrow, A). The lesion is nearly isointense on the LSDI (2736/89/1; b = 600 s/mm2) trace image (B), and has a slightly increased ADC on the ADC map (arrow, C), as indicated by mildly increased signal. The increased ADC confirms that this is not an acute infarction.
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