Tissue Response of a Small Saccular Aneurysm after Incomplete Occlusion with a Guglielmi Detachable Coil
Satoru Shimizu
,a,
Akira Kurataa,
Makoto Takanoa,
Hiroshi Takagia,
Hitoshi Yamazakia,
Yoshio Miyasakaa and
Kiyotaka Fujiia
a From the Department of Neurosurgery (S.S., A.K., Y.M., K.F.), Kitasato University, School of Medicine and the Departments of Neurosurgery (S.S., M.T. H.T.) and Pathology (H.Y.), Yamato City Hospital.
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FIG 1. A 49-year-old woman with a small saccular aneurysm.
A, Anteroposterior carotid angiogram shows the PTA (arrow) and a small saccular aneurysm at the basilar-superior cerebellar bifurcation (arrowhead).
B, Angiogram, after embolization with a GDC, shows partial opacification of the fundus of the aneurysm.
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FIG 2. Microscopic examination of the small saccular aneurysm after GDC occlusion.
A, Low-power photomicrograph shows a cross-section of the aneurysm at the fundus, with a fibrotic component (small star) adjacent to the aneurysmal wall (arrows) and an unformed thrombus at the center of the aneurysm (large star). The location of the coil is indicated (asterisk). (Azan stain; magnification x100)
B, Higher power magnification of the region adjacent to the wall shows fibrous connective tissue with rich capillaries. (Azan stain; magnification x200)
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