The Effect of Age on Odor-Stimulated Functional MR Imaging
David M. Yousem,a,
Joseph A. Maldjiana,
Thomas Hummela,
David C. Alsopa,
Rena J. Gecklea,
Michael A. Krauta and
Richard L. Dotya
a From the Department of Radiology (D.M.Y., J.A.M., D.C.A., R.J.G.) and the Smell and Taste Center (D.M.Y., T.H., R.J.G., R.L.D.), University of Pennsylvania Medical Center, Philadelphia; and the Department of Radiology, Johns Hopkins Hospital, Baltimore, MD (D.M.Y., M.A.K.).
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FIG 1. Older group functional MR imaging map (right is right side of brain).
A, Minimal right-sided perisylvian activation is noted (arrows).
B, Magnified view shows minimal activated volume (arrow).
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FIG 2. Activation map in single older subject. Left inferior frontal (straight arrows), right perisylvian (arrowheads), and right cingulate (curved arrow) areas show activation
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FIG 3. Younger group functional MR imaging map.
A, Set of group map images from younger subjects displayed in Talairach space such that the right side of the image is the right side of the brain and the left side of the image is the left side of the brain. Note the right-sided predominance of activation inferiorly in the frontal (arrowheads) and perisylvian (solid arrows) regions. Cingulate activation on the right is also prominent (open arrows).
B, Magnified view of one image from the group set shows the right perisylvian (solid arrow) and cingulate (open arrow) activation.
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FIG 4. Activation map in single younger subject. Note the avid activation in both inferior frontal lobes (arrowheads), right more than left. Perisylvian activation inferiorly on the right (open arrows) is also noteworthy.
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